Human 3D cellular model of hypoxic brain injury of prematurity
نویسندگان
چکیده
منابع مشابه
P6: Application of 3D Bioactive Scaffolds in Brain Injury
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متن کاملDiffusion Tensor Imaging of White Matter Injury Caused by Prematurity-Induced Hypoxic-Ischemic Brain Damage
BACKGROUND This investigation aimed to evaluate changes in apparent diffusion coefficient (ADC) and fractional anisotropy (FA) of white matter injury (WMI) in preterm neonates with hypoxic-ischemic encephalopathy (HIE) using diffusion tension imaging (DTI). MATERIAL AND METHODS Thirty-eight neonates less than 37 weeks of gestation with leukoencephalopathy (as observation group) and 38 full-term...
متن کاملA rat model of severe neonatal hypoxic-ischemic brain injury.
BACKGROUND AND PURPOSE Perinatal hypoxic-ischemic brain injury is a common problem with severe neurological sequelae. In this report we describe in detail a simple model of hypoxia-ischemia in the neonatal rat that gives rise to severe neocortical infarction and to selective hippocampal neuronal necrosis. METHODS Seven-day-old Simonsen Wistar rat pups underwent bilateral carotid artery ligati...
متن کاملp6: application of 3d bioactive scaffolds in brain injury
naturally the brain is ineffective in regenerating functional tissue after disease or injury, so to overcome these defects innovative curative strategies such as stem cell transplantation and tissue engineering have to be considered. researchers investigate the use of strategies to attain better functional repair results. one of the important challenges of effective transplantation is the deliv...
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ژورنال
عنوان ژورنال: Nature Medicine
سال: 2019
ISSN: 1078-8956,1546-170X
DOI: 10.1038/s41591-019-0436-0